How Does our Brain Know When to Eat and When to Stop?

The regulation of food intake is a complex concert of signals from different parts of our body, working together with our biological clock, and of course, our brain. Those signals (or messages) indicate for example whether our stomach is full or empty, if we have energy incoming, or how much energy we have stored in our fat cells. Eating also needs to be pleasurable. But who is coordinating all these different signals?